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PKC-induced Sensitization of Ca(2+)-dependent Exocytosis Is Mediated by Reducing the Ca(2+) Cooperativity in Pituitary Gonadotropes
The highly cooperative nature of Ca(2+)-dependent exocytosis is very important for the precise regulation of transmitter release. It is not known whether the number of binding sites on the Ca(2+) sensor can be modulated or not. We have previously reported that protein kinase C (PKC) activation sensi...
Autores principales: | Yang, Hua, Liu, Huisheng, Hu, Zhitao, Zhu, Hongliang, Xu, Tao |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234013/ https://www.ncbi.nlm.nih.gov/pubmed/15710914 http://dx.doi.org/10.1085/jgp.200409230 |
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