Hysteresis in the Voltage Dependence of HCN Channels: Conversion between Two Modes Affects Pacemaker Properties

Hyperpolarization-activated, cyclic nucleotide-gated (HCN) ion channels are important for rhythmic activity in the brain and in the heart. In this study, using ionic and gating current measurements, we show that cloned spHCN channels undergo a hysteresis in their voltage dependence during normal gat...

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Detalles Bibliográficos
Autores principales: Männikkö, Roope, Pandey, Shilpi, Larsson, H. Peter, Elinder, Fredrik
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234019/
https://www.ncbi.nlm.nih.gov/pubmed/15710913
http://dx.doi.org/10.1085/jgp.200409130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234019/
https://www.ncbi.nlm.nih.gov/pubmed/15710913
http://dx.doi.org/10.1085/jgp.200409130

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