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Y(3+) Block Demonstrates an Intracellular Activation Gate for the α1G T-type Ca(2+) Channel
Classical electrophysiology and contemporary crystallography suggest that the activation gate of voltage-dependent channels is on the intracellular side, but a more extracellular “pore gate” has also been proposed. We have used the voltage dependence of block by extracellular Y(3+) as a tool to loca...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234021/ https://www.ncbi.nlm.nih.gov/pubmed/15572343 http://dx.doi.org/10.1085/jgp.200409167 |