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Carboxy-terminal Determinants of Conductance in Inward-rectifier K Channels

Previous studies suggested that the cytoplasmic COOH-terminal portions of inward rectifier K channels could contribute significant resistance barriers to ion flow. To explore this question further, we exchanged portions of the COOH termini of ROMK2 (Kir1.1b) and IRK1 (Kir2.1) and measured the result...

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Detalles Bibliográficos
Autores principales: Zhang, Yu-Yang, Robertson, Janice L., Gray, Daniel A., Palmer, Lawrence G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234023/
https://www.ncbi.nlm.nih.gov/pubmed/15572348
http://dx.doi.org/10.1085/jgp.200409166