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On the Importance of Atomic Fluctuations, Protein Flexibility, and Solvent in Ion Permeation
Proteins, including ion channels, often are described in terms of some average structure and pictured as rigid entities immersed in a featureless solvent continuum. This simplified view, which provides for a convenient representation of the protein's overall structure, incurs the risk of deemph...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234034/ https://www.ncbi.nlm.nih.gov/pubmed/15572347 http://dx.doi.org/10.1085/jgp.200409111 |