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On the Importance of Atomic Fluctuations, Protein Flexibility, and Solvent in Ion Permeation

Proteins, including ion channels, often are described in terms of some average structure and pictured as rigid entities immersed in a featureless solvent continuum. This simplified view, which provides for a convenient representation of the protein's overall structure, incurs the risk of deemph...

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Detalles Bibliográficos
Autores principales: Allen, Toby W., Andersen, O.S., Roux, Benoit
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234034/
https://www.ncbi.nlm.nih.gov/pubmed/15572347
http://dx.doi.org/10.1085/jgp.200409111