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Maurer's clefts of Plasmodium falciparum are secretory organelles that concentrate virulence protein reporters for delivery to the host erythrocyte

In blood-stage infection by the human malaria parasite Plasmodium falciparum, export of proteins from the intracellular parasite to the erythrocyte is key to virulence. This export is mediated by a host-targeting (HT) signal present on a “secretome” of hundreds of parasite proteins engaged in remode...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Souvik, van Ooij, Christiaan, Balu, Bharath, Adams, John H., Haldar, Kasturi
Formato: Texto
Lenguaje:English
Publicado: American Society of Hematology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234068/
https://www.ncbi.nlm.nih.gov/pubmed/18057226
http://dx.doi.org/10.1182/blood-2007-09-115279