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Two Stable, Conducting Conformations of the Selectivity Filter in Shaker K(+) Channels

We have examined the voltage dependence of external TEA block of Shaker K(+) channels over a range of internal K(+) concentrations from 2 to 135 mM. We found that the concentration dependence of external TEA block in low internal K(+) solutions could not be described by a single TEA binding affinity...

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Detalles Bibliográficos
Autores principales: Thompson, Jill, Begenisich, Ted
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234082/
https://www.ncbi.nlm.nih.gov/pubmed/15897293
http://dx.doi.org/10.1085/jgp.200509251