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Two Stable, Conducting Conformations of the Selectivity Filter in Shaker K(+) Channels
We have examined the voltage dependence of external TEA block of Shaker K(+) channels over a range of internal K(+) concentrations from 2 to 135 mM. We found that the concentration dependence of external TEA block in low internal K(+) solutions could not be described by a single TEA binding affinity...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234082/ https://www.ncbi.nlm.nih.gov/pubmed/15897293 http://dx.doi.org/10.1085/jgp.200509251 |