Computational analysis of splicing errors and mutations in human transcripts

BACKGROUND: Most retained introns found in human cDNAs generated by high-throughput sequencing projects seem to result from underspliced transcripts, and thus they capture intermediate steps of pre-mRNA splicing. On the other hand, mutations in splice sites cause exon skipping of the respective exon...

Descripción completa

Detalles Bibliográficos
Autores principales: Kurmangaliyev, Yerbol Z, Gelfand, Mikhail S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234086/
https://www.ncbi.nlm.nih.gov/pubmed/18194514
http://dx.doi.org/10.1186/1471-2164-9-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234086/
https://www.ncbi.nlm.nih.gov/pubmed/18194514
http://dx.doi.org/10.1186/1471-2164-9-13

Ejemplares similares