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Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5α

TRIM5 proteins constitute a class of restriction factors that prevent host cell infection by retroviruses from different species. TRIM5α restricts retroviral infection early after viral entry, before the generation of viral reverse transcription products. However, the underlying restriction mechanis...

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Detalles Bibliográficos
Autores principales: Campbell, Edward M., Perez, Omar, Anderson, Jenny L., Hope, Thomas J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234241/
https://www.ncbi.nlm.nih.gov/pubmed/18250195
http://dx.doi.org/10.1083/jcb.200706154