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Binding of cargo sorting signals to AP-1 enhances its association with ADP ribosylation factor 1–GTP

The adaptor protein AP-1 is the major coat protein involved in the formation of clathrin-coated vesicles at the trans-Golgi network. The prevailing view is that AP-1 recruitment involves coincident binding to multiple low-affinity sites comprising adenosine diphosphate ribosylation factor 1 (Arf-1)–...

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Detalles Bibliográficos
Autores principales: Lee, Intaek, Doray, Balraj, Govero, Jennifer, Kornfeld, Stuart
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234244/
https://www.ncbi.nlm.nih.gov/pubmed/18250197
http://dx.doi.org/10.1083/jcb.200709037