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Human CMV infection induces 5-lipoxygenase expression and leukotriene B(4) production in vascular smooth muscle cells

Leukotrienes (LTs) are powerful proinflammatory lipid mediators that may play a central role in cardiovascular diseases, including arteriosclerosis, myocardial infarction, and stroke. Owing to restricted expression of 5-lipoxygenase (5-LO), the enzyme required for their synthesis, LTs are almost exc...

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Detalles Bibliográficos
Autores principales: Qiu, Hong, Strååt, Klas, Rahbar, Afsar, Wan, Min, Söderberg-Nauclér, Cecilia, Haeggström, Jesper Z.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234367/
https://www.ncbi.nlm.nih.gov/pubmed/18180307
http://dx.doi.org/10.1084/jem.20070201