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MerTK is required for apoptotic cell–induced T cell tolerance

Self-antigens expressed by apoptotic cells (ACs) may become targets for autoimmunity. Tolerance to these antigens is partly established by an ill-defined capacity of ACs to inhibit antigen-presenting cells such as dendritic cells (DCs). We present evidence that the receptor tyrosine kinase Mer (MerT...

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Detalles Bibliográficos
Autores principales: Wallet, Mark A., Sen, Pradip, Flores, Rafael R., Wang, Yaming, Yi, Zuoan, Huang, Yingsu, Mathews, Clayton E., Earp, H. Shelton, Matsushima, Glenn, Wang, Bo, Tisch, Roland
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234377/
https://www.ncbi.nlm.nih.gov/pubmed/18195070
http://dx.doi.org/10.1084/jem.20062293