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MerTK is required for apoptotic cell–induced T cell tolerance
Self-antigens expressed by apoptotic cells (ACs) may become targets for autoimmunity. Tolerance to these antigens is partly established by an ill-defined capacity of ACs to inhibit antigen-presenting cells such as dendritic cells (DCs). We present evidence that the receptor tyrosine kinase Mer (MerT...
Autores principales: | Wallet, Mark A., Sen, Pradip, Flores, Rafael R., Wang, Yaming, Yi, Zuoan, Huang, Yingsu, Mathews, Clayton E., Earp, H. Shelton, Matsushima, Glenn, Wang, Bo, Tisch, Roland |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234377/ https://www.ncbi.nlm.nih.gov/pubmed/18195070 http://dx.doi.org/10.1084/jem.20062293 |
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