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Evidence for the tonic inhibition of spinal pain by nicotinic cholinergic transmission through primary afferents

BACKGROUND: We have proposed that nerve injury-specific loss of spinal tonic cholinergic inhibition may play a role in the analgesic effects of nicotinic acetylcholine receptor (nAChR) agonists on neuropathic pain. However, the tonic cholinergic inhibition of pain remains to be well characterized. R...

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Detalles Bibliográficos
Autores principales: Matsumoto, Misaki, Xie, Weijiao, Inoue, Makoto, Ueda, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234393/
https://www.ncbi.nlm.nih.gov/pubmed/18088441
http://dx.doi.org/10.1186/1744-8069-3-41