Platelet-derived growth factor receptor-β, carrying the activating mutation D849N, accelerates the establishment of B16 melanoma

BACKGROUND: Platelet-derived growth factor (PDGF)-BB and PDGF receptor (PDGFR)-β are mainly expressed in the developing vasculature, where PDGF-BB is produced by endothelial cells and PDGFR-β is expressed by mural cells, including pericytes. PDGF-BB is produced by most types of solid tumors, and PDG...

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Detalles Bibliográficos
Autores principales: Suzuki, Shioto, Heldin, Carl-Henrik, Heuchel, Rainer Lothar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234427/
https://www.ncbi.nlm.nih.gov/pubmed/18076756
http://dx.doi.org/10.1186/1471-2407-7-224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234427/
https://www.ncbi.nlm.nih.gov/pubmed/18076756
http://dx.doi.org/10.1186/1471-2407-7-224

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