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Platelet-derived growth factor receptor-β, carrying the activating mutation D849N, accelerates the establishment of B16 melanoma

BACKGROUND: Platelet-derived growth factor (PDGF)-BB and PDGF receptor (PDGFR)-β are mainly expressed in the developing vasculature, where PDGF-BB is produced by endothelial cells and PDGFR-β is expressed by mural cells, including pericytes. PDGF-BB is produced by most types of solid tumors, and PDG...

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Detalles Bibliográficos
Autores principales:	Suzuki, Shioto, Heldin, Carl-Henrik, Heuchel, Rainer Lothar
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234427/ https://www.ncbi.nlm.nih.gov/pubmed/18076756 http://dx.doi.org/10.1186/1471-2407-7-224

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