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Characterization of anticoagulant heparinoids by immunoprofiling

Heparinoids are used in the clinic as anticoagulants. A specific pentasaccharide in heparinoids activates antithrombin III, resulting in inactivation of factor Xa and–when additional saccharides are present–inactivation of factor IIa. Structural and functional analysis of the heterogeneous heparinoi...

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Detalles Bibliográficos
Autores principales: Wijnhoven, Tessa J., van de Westerlo, Els M., Smits, Nicole C., Lensen, Joost F., Rops, Angelique L., van der Vlag, Johan, Berden, Jo H., van den Heuvel, Lambert P., van Kuppevelt, Toin H.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234449/
https://www.ncbi.nlm.nih.gov/pubmed/17909966
http://dx.doi.org/10.1007/s10719-007-9070-z