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Synergistic Activation of ENaC by Three Membrane-bound Channel-activating Serine Proteases (mCAP1, mCAP2, and mCAP3) and Serum- and Glucocorticoid-regulated Kinase (Sgk1) in Xenopus Oocytes

Sodium balance is maintained by the precise regulation of the activity of the epithelial sodium channel (ENaC) in the kidney. We have recently reported an extracellular activation of ENaC-mediated sodium transport (I(Na)) by a GPI-anchored serine protease (mouse channel–activating protein, mCAP1) th...

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Detalles Bibliográficos
Autores principales: Vuagniaux, Grégoire, Vallet, Véronique, Jaeger, Nicole Fowler, Hummler, Edith, Rossier, Bernard C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234457/
https://www.ncbi.nlm.nih.gov/pubmed/12149280
http://dx.doi.org/10.1085/jgp.20028598