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Interaction of A2E with Model Membranes. Implications to the Pathogenesis of Age-related Macular Degeneration
Deposition of a fluorophoric material, known as lipofuscin, in retinal pigment epithelium cells has been speculated to be one of the biomarkers of age-related macular degeneration. One of the fluorophores of lipofuscin has been characterized as A2E, a pyridinium bisretinoid. Its cationic nature alon...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234466/ https://www.ncbi.nlm.nih.gov/pubmed/12149277 http://dx.doi.org/10.1085/jgp.20028566 |