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Low pH Potentiates Both Capsaicin Binding and Channel Gating of VR1 Receptors

Capsaicin ion channels are highly expressed in peripheral nervous terminals and involved in pain and thermal sensations. One characteristic of the cloned VR1 receptor is its multimodal responses to various types of noxious stimuli. The channel is independently activated by capsaicin and related vani...

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Detalles Bibliográficos
Autores principales: Ryu, Sujung, Liu, Beiying, Qin, Feng
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234467/
https://www.ncbi.nlm.nih.gov/pubmed/12835470
http://dx.doi.org/10.1085/jgp.200308847