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Mapping the BK(Ca) Channel's “Ca(2+) Bowl”: Side-chains Essential for Ca(2+) Sensing

There is controversy over whether Ca(2+) binds to the BK(Ca) channel's intracellular domain or its integral-membrane domain and over whether or not mutations that reduce the channel's Ca(2+) sensitivity act at the point of Ca(2+) coordination. One region in the intracellular domain that ha...

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Detalles Bibliográficos
Autores principales: Bao, Lin, Kaldany, Christina, Holmstrand, Ericka C., Cox, Daniel H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234491/
https://www.ncbi.nlm.nih.gov/pubmed/15111643
http://dx.doi.org/10.1085/jgp.200409052