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Molecular Basis of pH and Ca(2+) Regulation of Aquaporin Water Permeability
Aquaporins facilitate the diffusion of water across cell membranes. We previously showed that acid pH or low Ca(2+) increase the water permeability of bovine AQP0 expressed in Xenopus oocytes. We now show that external histidines in loops A and C mediate the pH dependence. Furthermore, the position...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234493/ https://www.ncbi.nlm.nih.gov/pubmed/15078916 http://dx.doi.org/10.1085/jgp.200308990 |