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Inhibition and Redistribution of NHE3, the Apical Na(+)/H(+) Exchanger, by Clostridium difficile Toxin B
NHE3, the apical isoform of the Na(+)/H(+) exchanger, is central to the absorption of salt and water across the intestinal epithelium. We report that treatment of epithelial cells with toxin B of Clostridium difficile, a diarrheal pathogen, causes a pronounced inhibition of NHE3 activity, with littl...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234495/ https://www.ncbi.nlm.nih.gov/pubmed/15078917 http://dx.doi.org/10.1085/jgp.200308979 |