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Calcium Regulation of Single Ryanodine Receptor Channel Gating Analyzed Using HMM/MCMC Statistical Methods

Type-II ryanodine receptor channels (RYRs) play a fundamental role in intracellular Ca(2+) dynamics in heart. The processes of activation, inactivation, and regulation of these channels have been the subject of intensive research and the focus of recent debates. Typically, approaches to understand t...

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Detalles Bibliográficos
Autores principales: Rosales, Rafael A., Fill, Michael, Escobar, Ariel L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234502/
https://www.ncbi.nlm.nih.gov/pubmed/15111644
http://dx.doi.org/10.1085/jgp.200308868