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Antagonistic Regulation of Native Ca(2+)- and ATP-sensitive Cation Channels in Brain Capillaries by Nucleotides and Decavanadate

Regulation by cytosolic nucleotides of Ca(2+)- and ATP-sensitive nonselective cation channels (CA-NSCs) in rat brain capillary endothelial cells was studied in excised inside-out patches. Open probability (P(o)) was suppressed by cytosolic nucleotides with apparent K(I) values of 17, 9, and 2 μM for...

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Detalles Bibliográficos
Autores principales: Csanády, László, Adam-Vizi, Vera
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234573/
https://www.ncbi.nlm.nih.gov/pubmed/15173222
http://dx.doi.org/10.1085/jgp.200309008