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Polyglutamine Genes Interact to Modulate the Severity and Progression of Neurodegeneration in Drosophila
The expansion of polyglutamine tracts in a variety of proteins causes devastating, dominantly inherited neurodegenerative diseases, including six forms of spinal cerebellar ataxia (SCA). Although a polyglutamine expansion encoded in a single allele of each of the responsible genes is sufficient for...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2235903/ https://www.ncbi.nlm.nih.gov/pubmed/18271626 http://dx.doi.org/10.1371/journal.pbio.0060029 |