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IL-18 Does not Increase Allergic Airway Disease in Mice When Produced by BCG

Whilst BCG inhibits allergic airway responses in murine models, IL-18 has adversary effects depending on its environment. We therefore constructed a BCG strain producing murine IL-18 (BCG-IL-18) and evaluated its efficiency to prevent an asthma-like reaction in mice. BALB/cByJ mice were sensitized (...

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Detalles Bibliográficos
Autores principales: Amniai, L., Biet, F., Marquillies, P., Locht, C., Pestel, J., Tonnel, A.-B., Duez, C.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2235931/
https://www.ncbi.nlm.nih.gov/pubmed/18299704
http://dx.doi.org/10.1155/2007/67276