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Current-dependent Block of Rabbit Sino-Atrial Node I(f) Channels by Ivabradine

“Funny” (f-) channels have a key role in generation of spontaneous activity of pacemaker cells and mediate autonomic control of cardiac rate; f-channels and the related neuronal h-channels are composed of hyperpolarization-activated, cyclic nucleotide–gated (HCN) channel subunits. We have investigat...

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Detalles Bibliográficos
Autores principales: Bucchi, Annalisa, Baruscotti, Mirko, DiFrancesco, Dario
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238187/
https://www.ncbi.nlm.nih.gov/pubmed/12084770
http://dx.doi.org/10.1085/jgp.20028593