Knorr-Rabe partial reduction of pyrroles: Application to the synthesis of indolizidine alkaloids

BACKGROUND: The Birch reduction of electron rich pyrroles does not occur readily. However, dissolving metal reduction with zinc under acidic conditions gives 3-pyrrolines (2,5-dihydropyrroles) in reasonable yield. This dissolving metal reduction was first reported by Knorr and Rabe in 1901 but since...

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Detalles Bibliográficos
Autores principales: Gourlay, Brendon S, Ryan, John H, Smith, Jason A
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2008
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238744/
https://www.ncbi.nlm.nih.gov/pubmed/18197983
http://dx.doi.org/10.1186/1860-5397-4-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238744/
https://www.ncbi.nlm.nih.gov/pubmed/18197983
http://dx.doi.org/10.1186/1860-5397-4-3

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