Threshold-dominated regulation hides genetic variation in gene expression networks

BACKGROUND: In dynamical models with feedback and sigmoidal response functions, some or all variables have thresholds around which they regulate themselves or other variables. A mathematical analysis has shown that when the dose-response functions approach binary or on/off responses, any variable wi...

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Detalles Bibliográficos
Autores principales: Gjuvsland, Arne B, Plahte, Erik, Omholt, Stig W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238762/
https://www.ncbi.nlm.nih.gov/pubmed/18062810
http://dx.doi.org/10.1186/1752-0509-1-57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238762/
https://www.ncbi.nlm.nih.gov/pubmed/18062810
http://dx.doi.org/10.1186/1752-0509-1-57

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