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Threshold-dominated regulation hides genetic variation in gene expression networks
BACKGROUND: In dynamical models with feedback and sigmoidal response functions, some or all variables have thresholds around which they regulate themselves or other variables. A mathematical analysis has shown that when the dose-response functions approach binary or on/off responses, any variable wi...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238762/ https://www.ncbi.nlm.nih.gov/pubmed/18062810 http://dx.doi.org/10.1186/1752-0509-1-57 |