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A structural analysis of in vitro catalytic activities of hammerhead ribozymes

BACKGROUND: Ribozymes are small catalytic RNAs that possess the dual functions of sequence-specific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit translation of genes at the messenger RNA (mRNA) level in both eukaryotic and prokaryotic systems and are thus useful t...

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Detalles Bibliográficos
Autores principales: Shao, Yu, Wu, Susan, Chan, Chi Yu, Klapper, Jessie R, Schneider, Erasmus, Ding, Ye
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238771/
https://www.ncbi.nlm.nih.gov/pubmed/18053134
http://dx.doi.org/10.1186/1471-2105-8-469