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A structural analysis of in vitro catalytic activities of hammerhead ribozymes

BACKGROUND: Ribozymes are small catalytic RNAs that possess the dual functions of sequence-specific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit translation of genes at the messenger RNA (mRNA) level in both eukaryotic and prokaryotic systems and are thus useful t...

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Detalles Bibliográficos
Autores principales:	Shao, Yu, Wu, Susan, Chan, Chi Yu, Klapper, Jessie R, Schneider, Erasmus, Ding, Ye
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238771/ https://www.ncbi.nlm.nih.gov/pubmed/18053134 http://dx.doi.org/10.1186/1471-2105-8-469

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