Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

Protein kinase autophosphorylation of activation segment residues is a common regulatory mechanism in phosphorylation-dependent signalling cascades. However, the molecular mechanisms that guarantee specific and efficient phosphorylation of these sites have not been elucidated. Here, we report on thr...

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Detalles Bibliográficos
Autores principales: Pike, Ashley C W, Rellos, Peter, Niesen, Frank H, Turnbull, Andrew, Oliver, Antony W, Parker, Sirlester A, Turk, Benjamin E, Pearl, Laurence H, Knapp, Stefan
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2239268/
https://www.ncbi.nlm.nih.gov/pubmed/18239682
http://dx.doi.org/10.1038/emboj.2008.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2239268/
https://www.ncbi.nlm.nih.gov/pubmed/18239682
http://dx.doi.org/10.1038/emboj.2008.8

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