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Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites
Protein kinase autophosphorylation of activation segment residues is a common regulatory mechanism in phosphorylation-dependent signalling cascades. However, the molecular mechanisms that guarantee specific and efficient phosphorylation of these sites have not been elucidated. Here, we report on thr...
Autores principales: | Pike, Ashley C W, Rellos, Peter, Niesen, Frank H, Turnbull, Andrew, Oliver, Antony W, Parker, Sirlester A, Turk, Benjamin E, Pearl, Laurence H, Knapp, Stefan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2239268/ https://www.ncbi.nlm.nih.gov/pubmed/18239682 http://dx.doi.org/10.1038/emboj.2008.8 |
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