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SV-IV Peptide1–16 reduces coagulant power in normal Factor V and Factor V Leiden

Native Factor V is an anticoagulant, but when activated by thrombin, Factor X or platelet proteases, it becomes a procoagulant. Due to these double properties, Factor V plays a crucial role in the regulation of coagulation/anticoagulation balance. Factor V Leiden (FVL) disorder may lead to thromboph...

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Detalles Bibliográficos
Autores principales: Di Micco, Biagio, Lepretti, Marilena, Rota, Lidia, Quaglia, Ilaria, Ferrazzi, Paola, Di Micco, Gianluca, Di Micco, Pierpaolo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241586/
https://www.ncbi.nlm.nih.gov/pubmed/18154667
http://dx.doi.org/10.1186/1479-5876-5-69