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SV-IV Peptide1–16 reduces coagulant power in normal Factor V and Factor V Leiden
Native Factor V is an anticoagulant, but when activated by thrombin, Factor X or platelet proteases, it becomes a procoagulant. Due to these double properties, Factor V plays a crucial role in the regulation of coagulation/anticoagulation balance. Factor V Leiden (FVL) disorder may lead to thromboph...
Автори: | , , , , , , |
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Формат: | Текст |
Мова: | English |
Опубліковано: |
BioMed Central
2007
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Предмети: | |
Онлайн доступ: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241586/ https://www.ncbi.nlm.nih.gov/pubmed/18154667 http://dx.doi.org/10.1186/1479-5876-5-69 |