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Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH
BACKGROUND: Insulin is a therapeutic protein that is widely used for the treatment of diabetes. Its biological function was discovered more than 80 years ago and it has since then been characterized extensively. Crystallization of the insulin molecule has always been a key activity since the protein...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241603/ https://www.ncbi.nlm.nih.gov/pubmed/18093308 http://dx.doi.org/10.1186/1472-6807-7-83 |