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A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm

BACKGROUND: Intrabodies are defined as antibody molecules which are ectopically expressed inside the cell. Such intrabodies can be used to visualize or inhibit the targeted antigen in living cells. However, most antibody fragments cannot be used as intrabodies because they do not fold under the redu...

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Detalles Bibliográficos
Autores principales: Philibert, Pascal, Stoessel, Audrey, Wang, Wei, Sibler, Annie-Paule, Bec, Nicole, Larroque, Christian, Saven, Jeffery G, Courtête, Jérôme, Weiss, Etienne, Martineau, Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241821/
https://www.ncbi.nlm.nih.gov/pubmed/18034894
http://dx.doi.org/10.1186/1472-6750-7-81