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DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences
Microsatellites are ubiquitously present in eukaryotic genomes and are implicated as positive factors in evolution. At the nucleotide level, microsatellites undergo slippage events that alter allele length and base changes that interrupt the repetitive tract. We examined DNA polymerase errors within...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241860/ https://www.ncbi.nlm.nih.gov/pubmed/18079151 http://dx.doi.org/10.1093/nar/gkm1089 |