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Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives

Ribonuclease P (RNase P) is a Mg(2+)-dependent endoribonuclease responsible for the 5′-maturation of transfer RNAs. It is a ribonucleoprotein complex containing an essential RNA and a varying number of protein subunits depending on the source: at least one, four and nine in Bacteria, Archaea and Euk...

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Detalles Bibliográficos
Autores principales: Kawamoto, Steven A., Sudhahar, Christopher G., Hatfield, Cynthia L., Sun, Jing, Behrman, Edward J., Gopalan, Venkat
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241863/
https://www.ncbi.nlm.nih.gov/pubmed/18084035
http://dx.doi.org/10.1093/nar/gkm1088