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Interplay of ion binding and attraction in DNA condensed by multivalent cations

We have measured forces generated by multivalent cation-induced DNA condensation using single-molecule magnetic tweezers. In the presence of cobalt hexammine, spermidine, or spermine, stretched DNA exhibits an abrupt configurational change from extended to condensed. This occurs at a well-defined co...

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Detalles Bibliográficos
Autores principales: Todd, Brian A., Rau, Donald C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241864/
https://www.ncbi.nlm.nih.gov/pubmed/18048417
http://dx.doi.org/10.1093/nar/gkm1038