Indirect readout in drug-DNA recognition: role of sequence-dependent DNA conformation

DNA-binding drugs have numerous applications in the engineered gene regulation. However, the drug-DNA recognition mechanism is poorly understood. Drugs can recognize specific DNA sequences not only through direct contacts but also indirectly through sequence-dependent conformation, in a similar mann...

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Detalles Bibliográficos
Autores principales: Araúzo-Bravo, Marcos J., Sarai, Akinori
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241865/
https://www.ncbi.nlm.nih.gov/pubmed/18039704
http://dx.doi.org/10.1093/nar/gkm892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241865/
https://www.ncbi.nlm.nih.gov/pubmed/18039704
http://dx.doi.org/10.1093/nar/gkm892

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