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Indirect readout in drug-DNA recognition: role of sequence-dependent DNA conformation
DNA-binding drugs have numerous applications in the engineered gene regulation. However, the drug-DNA recognition mechanism is poorly understood. Drugs can recognize specific DNA sequences not only through direct contacts but also indirectly through sequence-dependent conformation, in a similar mann...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241865/ https://www.ncbi.nlm.nih.gov/pubmed/18039704 http://dx.doi.org/10.1093/nar/gkm892 |