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Functional endogenous LINE-1 retrotransposons are expressed and mobilized in rat chloroleukemia cells

LINE-1 (L1) is a highly successful autonomous non-LTR retrotransposon and a major force shaping mammalian genomes. Although there are about 600 000 L1 copies covering 23% of the rat genome, full-length rat L1s (L1Rn) with intact open reading frames (ORFs) representing functional master copies for re...

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Detalles Bibliográficos
Autores principales: Kirilyuk, Alexander, Tolstonog, Genrich V., Damert, Annette, Held, Ulrike, Hahn, Silvia, Löwer, Roswitha, Buschmann, Christian, Horn, Axel V., Traub, Peter, Schumann, Gerald G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241872/
https://www.ncbi.nlm.nih.gov/pubmed/18073200
http://dx.doi.org/10.1093/nar/gkm1045