ATR-dependent pathways control hEXO1 stability in response to stalled forks

Nucleases play important roles in DNA synthesis, recombination and repair. We have previously shown that human exonuclease 1 (hEXO1) is phosphorylated in response to agents stalling DNA replication and that hEXO1 consequently undergoes ubiquitination and degradation in a proteasome-dependent manner....

Descripción completa

Detalles Bibliográficos
Autores principales: El-Shemerly, Mahmoud, Hess, Daniel, Pyakurel, Aswin K., Moselhy, Said, Ferrari, Stefano
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241874/
https://www.ncbi.nlm.nih.gov/pubmed/18048416
http://dx.doi.org/10.1093/nar/gkm1052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241874/
https://www.ncbi.nlm.nih.gov/pubmed/18048416
http://dx.doi.org/10.1093/nar/gkm1052

Ejemplares similares