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ATR-dependent pathways control hEXO1 stability in response to stalled forks
Nucleases play important roles in DNA synthesis, recombination and repair. We have previously shown that human exonuclease 1 (hEXO1) is phosphorylated in response to agents stalling DNA replication and that hEXO1 consequently undergoes ubiquitination and degradation in a proteasome-dependent manner....
Autores principales: | El-Shemerly, Mahmoud, Hess, Daniel, Pyakurel, Aswin K., Moselhy, Said, Ferrari, Stefano |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241874/ https://www.ncbi.nlm.nih.gov/pubmed/18048416 http://dx.doi.org/10.1093/nar/gkm1052 |
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