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Probing dynamics of HIV-1 nucleocapsid protein/target hexanucleotide complexes by 2-aminopurine

The nucleocapsid protein (NC) plays an important role in HIV-1, mainly through interactions with the genomic RNA and its DNA copies. Though the structures of several complexes of NC with oligonucleotides (ODNs) are known, detailed information on the ODN dynamics in the complexes is missing. To addre...

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Detalles Bibliográficos
Autores principales: Avilov, S. V., Piemont, E., Shvadchak, V., de Rocquigny, H., Mély, Y.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241888/
https://www.ncbi.nlm.nih.gov/pubmed/18086707
http://dx.doi.org/10.1093/nar/gkm1109