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2′-Methylseleno-modified oligoribonucleotides for X-ray crystallography synthesized by the ACE RNA solid-phase approach

Site-specifically modified 2′-methylseleno RNA represents a valuable derivative for phasing of X-ray crystallographic data. Several successful applications in three-dimensional structure determination of nucleic acids, such as the Diels–Alder ribozyme, have relied on this modification. Here, we intr...

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Detalles Bibliográficos
Autores principales: Puffer, Barbara, Moroder, Holger, Aigner, Michaela, Micura, Ronald
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241898/
https://www.ncbi.nlm.nih.gov/pubmed/18096613
http://dx.doi.org/10.1093/nar/gkm880