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Diversity of preferred nucleotide sequences around the translation initiation codon in eukaryote genomes

Understanding regulatory mechanisms of protein synthesis in eukaryotes is essential for the accurate annotation of genome sequences. Kozak reported that the nucleotide sequence GCCGCC(A/G)CCAUGG (AUG is the initiation codon) was frequently observed in vertebrate genes and that this ‘consensus’ seque...

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Detalles Bibliográficos
Autores principales: Nakagawa, So, Niimura, Yoshihito, Gojobori, Takashi, Tanaka, Hiroshi, Miura, Kin-ichiro
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241899/
https://www.ncbi.nlm.nih.gov/pubmed/18086709
http://dx.doi.org/10.1093/nar/gkm1102